Quarterly report pursuant to Section 13 or 15(d)

5. Stockholders' Deficit (Details)

v2.4.1.9
5. Stockholders' Deficit (Details) (USD $)
3 Months Ended
Mar. 31, 2015
Series A [Member]  
Contractual life 4 years 1 month 6 days
Expected volatility 132.00%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= us-gaap_SeriesAMember
Risk-free interest rate 0.40%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= us-gaap_SeriesAMember
Exercise price $ 0.60pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= us-gaap_SeriesAMember
Fair value per warrant $ 0.03pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= us-gaap_SeriesAMember
Series A Affiliates [Member]  
Contractual life 3 years 1 month 6 days
Expected volatility 114.10%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesAOneMember
Risk-free interest rate 0.40%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesAOneMember
Exercise price $ 0.60pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesAOneMember
Fair value per warrant $ 0.03pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesAOneMember
Series B [Member]  
Contractual life 3 years 1 month 6 days
Expected volatility 114.10%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= us-gaap_SeriesBMember
Risk-free interest rate 0.40%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= us-gaap_SeriesBMember
Exercise price $ 0.60pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= us-gaap_SeriesBMember
Fair value per warrant $ 0.03pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= us-gaap_SeriesBMember
Series C [Member]  
Contractual life 5 years 1 month 6 days
Expected volatility 121.90%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesCMember
Risk-free interest rate 0.40%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesCMember
Exercise price $ 0.60pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesCMember
Fair value per warrant $ 0.03pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesCMember
Aug/Sep 2011 Notes [Member]  
Contractual life 2 years 1 month 6 days
Expected volatility 126.60%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_AugSep2011NotesMember
Risk-free interest rate 0.40%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_AugSep2011NotesMember
Exercise price $ 0.60pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_AugSep2011NotesMember
Fair value per warrant $ 0.03pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_AugSep2011NotesMember
Feb2012PIPE [Member]  
Contractual life 4 years 7 months 6 days
Expected volatility 126.60%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_Feb2012PIPEMember
Risk-free interest rate 0.40%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_Feb2012PIPEMember
Exercise price $ 0.60pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_Feb2012PIPEMember
Fair value per warrant $ 0.03pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_Feb2012PIPEMember
Series J warrants February 6, 2013 [Member]  
Contractual life 36 months
Expected volatility 141.80%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsFebruary62013Member
Risk-free interest rate 0.39%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsFebruary62013Member
Exercise price $ 0.40pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsFebruary62013Member
Fair value per warrant $ 0.36pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsFebruary62013Member
Series J warrants March 28, 2013 [Member]  
Contractual life 36 months
Expected volatility 144.30%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsMarch282013Member
Risk-free interest rate 0.36%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsMarch282013Member
Exercise price $ 0.40pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsMarch282013Member
Fair value per warrant $ 0.26pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsMarch282013Member
Series J warrants May 20, 2013 [Member]  
Contractual life 36 months
Expected volatility 147.00%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsMay202013Member
Risk-free interest rate 0.36%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsMay202013Member
Exercise price $ 0.40pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsMay202013Member
Fair value per warrant $ 0.30pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesJWarrantsMay202013Member
Series K Warrants December 12, 2013  
Contractual life 36 months
Expected volatility 136.10%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsDecember122013Member
Risk-free interest rate 0.39%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsDecember122013Member
Exercise price $ 0.31pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsDecember122013Member
Fair value per warrant $ 0.20pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsDecember122013Member
Series K Warrants January 29, 2014  
Contractual life 36 months
Expected volatility 152.40%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsJanuary292014Member
Risk-free interest rate 0.39%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsJanuary292014Member
Exercise price $ 0.31pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsJanuary292014Member
Fair value per warrant $ 0.30pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsJanuary292014Member
Series K Warrants February, 28 2014  
Contractual life 36 months
Expected volatility 152.70%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsFebruary282014Member
Risk-free interest rate 0.39%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsFebruary282014Member
Exercise price $ 0.43pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsFebruary282014Member
Fair value per warrant $ 0.37pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsFebruary282014Member
Series K Warrants June 30, 2014  
Contractual life 36 months
Expected volatility 153.90%pbio_ExpectedVolatility
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsJune302014Member
Risk-free interest rate 0.90%pbio_RiskfreeInterestRate
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsJune302014Member
Exercise price $ 0.38pbio_ExercisePrice
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsJune302014Member
Fair value per warrant $ 0.29pbio_FairValuePerWarrant
/ us-gaap_AuctionMarketPreferredSecuritiesStockSeriesAxis
= pbio_SeriesKWarrantsJune302014Member