Annual report pursuant to Section 13 and 15(d)

Shareholders Equity

v2.4.1.9
Shareholders Equity (USD $)
Series D Preferred Stock
USD ($)
Series G Preferred Stock
USD ($)
Series H Preferred Stock
USD ($)
Series H2 Preferred Stock
Series J Preferred Stock
USD ($)
Series K Preferred Stock
USD ($)
Common Stock
USD ($)
Warrant
USD ($)
Additional Paid-In Capital
USD ($)
Accumulated Deficit
USD ($)
Total
USD ($)
Beginning Balance - Amount at Dec. 31, 2012 $ 3us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesDPreferredStockMember
$ 1,453us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesGPreferredStockMember
                 
Beginning Balance - Shares at Dec. 31, 2012 300us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesDPreferredStockMember
145,320us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesGPreferredStockMember
                 
Stock-based compensation                 136,796us-gaap_ShareBasedCompensation
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   136,796us-gaap_ShareBasedCompensation
Fair value of common stock issued for services, Shares             875,000us-gaap_StockIssuedDuringPeriodSharesIssuedForServices
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Fair value of common stock issued for services, Amount             8,750us-gaap_StockIssuedDuringPeriodValueIssuedForServices
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   467,962us-gaap_StockIssuedDuringPeriodValueIssuedForServices
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   476,712us-gaap_StockIssuedDuringPeriodValueIssuedForServices
Offering costs for issuance of preferred stock                 (67,739)pbio_OfferingCostsForIssuanceOfPreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   (67,739)pbio_OfferingCostsForIssuanceOfPreferredStock
Issuance of warrants in connection short-term loans               73,647pbio_IssuanceOfWarrantsInConnectionShorttermLoans
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_WarrantMember
      73,647pbio_IssuanceOfWarrantsInConnectionShorttermLoans
Issuance of warrants for services, Amount               21,028pbio_IssuanceOfWarrantsForServices
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_WarrantMember
      21,028pbio_IssuanceOfWarrantsForServices
Beneficial conversion of issued preferred stock                 1,002,602pbio_BeneficialConversionOfIssuedPreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
(1,002,602)pbio_BeneficialConversionOfIssuedPreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
  
Issuance of Series J convertible preferred stock, Shares         5,088pbio_IssuanceOfSeriesJConvertiblePreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesJPreferredStockMember
           
Issuance of Series J convertible preferred stock, Amount         51pbio_IssuanceOfSeriesJConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesJPreferredStockMember
    885,309pbio_IssuanceOfSeriesJConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_WarrantMember
1,149,340pbio_IssuanceOfSeriesJConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   2,034,700pbio_IssuanceOfSeriesJConvertiblePreferredStockAmount
Issuance of Series K convertible preferred stock, Shares           4,000pbio_IssuanceOfSeriesKConvertiblePreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesKPreferredStockMember
         
Issuance of Series K convertible preferred stock, Amount           40pbio_IssuanceOfSeriesKConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesKPreferredStockMember
  271,422pbio_IssuanceOfSeriesKConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_WarrantMember
728,538pbio_IssuanceOfSeriesKConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
  1,000,000pbio_IssuanceOfSeriesKConvertiblePreferredStockAmount
Reclassification of conversion option liabilities                 141,704pbio_ReclassificationOfConversionOptionLiabilities
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   141,704pbio_ReclassificationOfConversionOptionLiabilities
Conversion of common stock to preferred stock, Shares     10,000pbio_ConversionOfCommonStockToPreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesHPreferredStockMember
      (1,000,000)pbio_ConversionOfCommonStockToPreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Conversion of common stock to preferred stock, Amount     100pbio_ConversionOfCommonStockToPreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesHPreferredStockMember
      (10,000)pbio_ConversionOfCommonStockToPreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   9,900pbio_ConversionOfCommonStockToPreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
     
Dividends earned on preferred stock, Amount                   (160,420)us-gaap_DividendsPreferredStockCash
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
(160,420)us-gaap_DividendsPreferredStockCash
Net loss                   (4,084,427)us-gaap_NetIncomeLoss
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
(4,084,427)us-gaap_NetIncomeLoss
Ending Balance, Amount at Dec. 31, 2013 3us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesDPreferredStockMember
1,453us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesGPreferredStockMember
100us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesHPreferredStockMember
  51us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesJPreferredStockMember
           
Ending Balance, Shares at Dec. 31, 2013 300us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesDPreferredStockMember
145,320us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesGPreferredStockMember
10,000us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesHPreferredStockMember
  5,088us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesJPreferredStockMember
           
Stock-based compensation                 101,125us-gaap_ShareBasedCompensation
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   101,125us-gaap_ShareBasedCompensation
Fair value of common stock issued for services, Shares             588,830us-gaap_StockIssuedDuringPeriodSharesIssuedForServices
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Fair value of common stock issued for services, Amount             5,888us-gaap_StockIssuedDuringPeriodValueIssuedForServices
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   208,304us-gaap_StockIssuedDuringPeriodValueIssuedForServices
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   214,192us-gaap_StockIssuedDuringPeriodValueIssuedForServices
Offering costs for issuance of preferred stock                 (8,000)pbio_OfferingCostsForIssuanceOfPreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   (8,000)pbio_OfferingCostsForIssuanceOfPreferredStock
Issuance of warrants in connection short-term loans               49,599pbio_IssuanceOfWarrantsInConnectionShorttermLoans
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_WarrantMember
      49,599pbio_IssuanceOfWarrantsInConnectionShorttermLoans
Issuance of warrants for services, Shares               93,488pbio_IssuanceOfWarrantsForServicesShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_WarrantMember
      93,488pbio_IssuanceOfWarrantsForServicesShares
Issuance of stock in lieu of cash for Board of Director fees, Shares           399pbio_IssuanceOfStockInLieuOfCashForBoardOfDirectorFeesShares
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesKPreferredStockMember
         
Issuance of stock in lieu of cash for Board of Director fees, Amount           3pbio_IssuanceOfStockInLieuOfCashForBoardOfDirectorFeesAmount
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesKPreferredStockMember
  24,578pbio_IssuanceOfStockInLieuOfCashForBoardOfDirectorFeesAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_WarrantMember
60,169pbio_IssuanceOfStockInLieuOfCashForBoardOfDirectorFeesAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   84,750pbio_IssuanceOfStockInLieuOfCashForBoardOfDirectorFeesAmount
Exercise of warrants, Shares             596,658pbio_ExerciseOfWarrantsShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Exercise of warrants, Amount             5,967pbio_ExerciseOfWarrantsAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   143,198pbio_ExerciseOfWarrantsAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   149,165pbio_ExerciseOfWarrantsAmount
Beneficial conversion of issued preferred stock                 1,495,415pbio_BeneficialConversionOfIssuedPreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
(1,495,415)pbio_BeneficialConversionOfIssuedPreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
 
Warrant reset, Shares             3,612,000pbio_WarrantResetShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Warrant reset, Amount             36,120pbio_WarrantResetAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
163,654pbio_WarrantResetAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_WarrantMember
662,745pbio_WarrantResetAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   862,519pbio_WarrantResetAmount
Conversion of Series G convertible preferred stock, Shares   (58,750)pbio_ConversionOfSeriesGConvertiblePreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesGPreferredStockMember
        587,500pbio_ConversionOfSeriesGConvertiblePreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Conversion of Series G convertible preferred stock, Amount   (587)pbio_ConversionOfSeriesGConvertiblePreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesGPreferredStockMember
        5,875pbio_ConversionOfSeriesGConvertiblePreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   (5,288)pbio_ConversionOfSeriesGConvertiblePreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
    
Conversion of Series J convertible preferred stock, Shares         (1,542)pbio_ConversionOfSeriesJConvertiblePreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesJPreferredStockMember
  1,541,000pbio_ConversionOfSeriesJConvertiblePreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Conversion of Series J convertible preferred stock, Amount         (15)pbio_ConversionOfSeriesJConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesJPreferredStockMember
  15,410pbio_ConversionOfSeriesJConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   (15,395)pbio_ConversionOfSeriesJConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
     
Conversion of Series K convertible preferred stock, Shares           (1,099)pbio_ConversionOfSeriesKConvertiblePreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesKPreferredStockMember
1,099,000pbio_ConversionOfSeriesKConvertiblePreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Conversion of Series K convertible preferred stock, Amount           (11)pbio_ConversionOfSeriesKConvertiblePreferredStock
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesKPreferredStockMember
10,990pbio_ConversionOfSeriesKConvertiblePreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   (10,979)pbio_ConversionOfSeriesKConvertiblePreferredStock
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
     
Conversion of debt for common stock, Shares             510,000pbio_ConversionOfDebtForCommonStockShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Conversion of debt for common stock, Amount             5,100pbio_ConversionOfDebtForCommonStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   131,400pbio_ConversionOfDebtForCommonStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   136,500pbio_ConversionOfDebtForCommonStockAmount
Issuance of Series K convertible preferred stock, Shares           8,176pbio_IssuanceOfSeriesKConvertiblePreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesKPreferredStockMember
         
Issuance of Series K convertible preferred stock, Amount           82pbio_IssuanceOfSeriesKConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesKPreferredStockMember
  654,845pbio_IssuanceOfSeriesKConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_WarrantMember
1,592,432pbio_IssuanceOfSeriesKConvertiblePreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   2,247,359pbio_IssuanceOfSeriesKConvertiblePreferredStockAmount
Reclassification of conversion option liabilities                 320,338pbio_ReclassificationOfConversionOptionLiabilities
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   320,338pbio_ReclassificationOfConversionOptionLiabilities
Conversion of common stock to preferred stock, Shares       21pbio_ConversionOfCommonStockToPreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesH2PreferredStockMember
    (2,100,000)pbio_ConversionOfCommonStockToPreferredStockShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Conversion of common stock to preferred stock, Amount             (21,000)pbio_ConversionOfCommonStockToPreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
   21,000pbio_ConversionOfCommonStockToPreferredStockAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
     
Reclassification of Series D warrant liability                 330,405pbio_ReclassificationOfSeriesDWarrantLiability
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   330,405pbio_ReclassificationOfSeriesDWarrantLiability
Dividends earned on preferred stock, Amount                   (143,771)us-gaap_DividendsPreferredStockCash
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
(143,771)us-gaap_DividendsPreferredStockCash
Issuance of common stock for preferred dividends, Shares             214,135pbio_IssuanceOfCommonStockForPreferredDividendsShares
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
       
Issuance of common stock for preferred dividends, Amount             2,141pbio_IssuanceOfCommonStockForPreferredDividendsAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
  80,774pbio_IssuanceOfCommonStockForPreferredDividendsAmount
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
   82,915pbio_IssuanceOfCommonStockForPreferredDividendsAmount
Net loss                   (4,612,540)us-gaap_NetIncomeLoss
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
(4,612,540)us-gaap_NetIncomeLoss
Ending Balance, Amount at Dec. 31, 2014 $ 3us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesDPreferredStockMember
$ 866us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesGPreferredStockMember
$ 100us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesHPreferredStockMember
  $ 36us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesJPreferredStockMember
$ 114us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesKPreferredStockMember
$ 186,734us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember
$ 5,253,566us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_WarrantMember
$ 24,617,564us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_AdditionalPaidInCapitalMember
$ (32,118,714)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_RetainedEarningsMember
$ (2,059,731)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
Ending Balance, Shares at Dec. 31, 2014 300us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesDPreferredStockMember
86,570us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesGPreferredStockMember
10,000us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_SeriesHPreferredStockMember
21us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesH2PreferredStockMember
3,546us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesJPreferredStockMember
11,416us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= pbio_SeriesKPreferredStockMember
18,673,390us-gaap_SharesIssued
/ us-gaap_StatementEquityComponentsAxis
= us-gaap_CommonStockMember