Pressure BioSciences, Inc. Annual report pursuant to Section 13 and 15(d)

Annual report pursuant to Section 13 and 15(d)

Subsequent Events (Details Narrative)

Subsequent Events (Details Narrative) - USD ($)					3 Months Ended	12 Months Ended
Subsequent Events (Details Narrative) - USD ($)	Sep. 25, 2021	Sep. 25, 2021	Dec. 23, 2020	Sep. 25, 2020	Mar. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Subsequent Event [Line Items]
Debt instrument, description			we are obligated to issue 100,000 warrants if the loan is not repaid before January 23, 2021 and an additional 10,000 shares of common stock and 100,000 warrants if the loan is not repaid before February 23, 2021. We are also obligated to issue 10,000 shares of common stock and 200,000 warrants if the loan is not repaid before March 23, 2021. During the year ended December 31, 2021 the Company issued 400,000 warrants to this lender ($3.50 exercise price and five-year term) with a fair value of $600,298. The Company is also obligated to issue 10,000 shares of common stock to this lender every 31 days up to the loan’s maturity date on June 23, 2021.			Loan is not convertible until 180 days from the date of issuance of the Note and following an Event of Default will be convertible at the lesser of $2.50 per share or 90% of the lowest trading price over the previous 20 days. The loan is guaranteed by the Company’s Chief Executive Officer, but the lender may only enforce this guarantee after certain conditions have been met, specifically after (i) the occurrence of an Event of Default (as defined in the Note), (ii) the failure of the Company to cure the Default in 10 business days, and (iii) a failure by the Company to issue, or cause to be issued, shares of its common stock upon submission by the lender of a notice of conversion
Proceeds from Convertible Debt						$ 5,514,250	$ 8,296,800
Debt Instrument, Term		3 years
Stock Issued During Period, Shares, New Issues						2,883,282
Debt Conversion, Original Debt, Amount						$ 1,705,455
Repayments of Convertible Debt				$ 134,805		1,833,295	$ 2,857,007
Option Indexed to Issuer's Equity, Strike Price		$ 3.50
Repayments of Debt						$ 1,833,295
Common Stock [Member]
Subsequent Event [Line Items]
Stock Issued During Period, Shares, New Issues	37,000						188,778
Warrant [Member]
Subsequent Event [Line Items]
Debt Conversion, Converted Instrument, Warrants or Options Issued	30,000
Lender [Member]
Subsequent Event [Line Items]
Stock Issued During Period, Shares, New Issues						140,200
Debt Conversion, Original Debt, Amount						$ 350,500
Three Loans [Member]
Subsequent Event [Line Items]
Debt instrument face amount						475,000
Five Convertible Loans [Member]
Subsequent Event [Line Items]
Debt instrument face amount						$ 1,045,000
Merchant Agreements [Member] \| Common Stock [Member]
Subsequent Event [Line Items]
Repayments of Debt	$ 107,000
Merchant Agreements [Member] \| Minimum [Member]
Subsequent Event [Line Items]
Debt, interest rate						9.30%
Merchant Agreements [Member] \| Maximum [Member]
Subsequent Event [Line Items]
Debt, interest rate						14.00%
Subsequent Event [Member]
Subsequent Event [Line Items]
Proceeds from loans					$ 145,487
Debt, interest rate					12.00%
Debt default description					One loan is convertible at $2.50 per share other than in an event of default otherwise upon an event of default, the conversion price will be at 75% of the lowest trading price for the common stock over five days before conversion. The other loan is convertible, upon an event of default, at 75% of the lowest trading price for the common stock over five days before conversion.
Debt Instrument, Convertible, Conversion Price					$ 2.50
Original issue discount percentage					10.00%
Debt instrument, description					In this time the Company also rolled over two loans totaling $475,000 (dated June 30, 2021, and June 28, 2021) into new loans totaling $1,200,000 with terms extended six to eight months. The Company issued 132,000 shares of common stock as origination fees for the new loans. Separately, during this period the Company extended five loans totaling $1,045,000 (dated July 16, 2021, June 30,2021, July 16, 2021, July 16, 2021 and July 16, 2021) for five to six months with new principal of $1,095,250 issuing 147,500 shares of common stock as extension fees.
Subsequent Event [Member] \| Three Loans [Member]
Subsequent Event [Line Items]
Debt instrument face amount					$ 1,200,000
[custom:StockIssuedDuringPeriodSharesNewIssuesForOriginationFee]					132,000
Subsequent Event [Member] \| Three Loans [Member] \| Minimum [Member]
Subsequent Event [Line Items]
Debt Instrument, Term					6 months
Subsequent Event [Member] \| Three Loans [Member] \| Maximum [Member]
Subsequent Event [Line Items]
Debt Instrument, Term					8 months
Subsequent Event [Member] \| Five Convertible Loans [Member]
Subsequent Event [Line Items]
[custom:CommonStockForInterestAndExtensionFees]					$ 1,095,250
[custom:StockIssuedDuringPeriodSharesNewIssuesForExtensionFee]					147,500
Subsequent Event [Member] \| Five Convertible Loans [Member] \| Minimum [Member]
Subsequent Event [Line Items]
Debt Instrument, Term					5 months
Subsequent Event [Member] \| Five Convertible Loans [Member] \| Maximum [Member]
Subsequent Event [Line Items]
Debt Instrument, Term					6 months
Subsequent Event [Member] \| Merchant Agreements [Member]
Subsequent Event [Line Items]
Debt instrument, description					Merchant Cash lender agreements (collecting $361,120 and obligating the Company to pay $18,990 each week to the lenders
Subsequent Event [Member] \| Merchant Cash Lender Agreements [Member]
Subsequent Event [Line Items]
Proceeds from Convertible Debt					$ 361,120
Subsequent Event [Member] \| Convertible Debt [Member]
Subsequent Event [Line Items]
Related Party Transaction, Due from (to) Related Party, Current					177,500
Obligating to pay week to the lenders					$ 18,990