Pressure BioSciences, Inc. Annual report pursuant to Section 13 and 15(d)

Annual report pursuant to Section 13 and 15(d)

Stockholders' (Deficit) (Details Narrative)

Stockholders' (Deficit) (Details Narrative) - USD ($)												1 Months Ended		12 Months Ended
Stockholders' (Deficit) (Details Narrative) - USD ($)	Dec. 23, 2020	Dec. 19, 2019	May 10, 2017	Dec. 23, 2014	May 30, 2013	Mar. 28, 2013	Feb. 06, 2013	Jan. 04, 2013	Nov. 15, 2012	Jul. 06, 2012	Nov. 11, 2011	Dec. 31, 2013	Apr. 30, 2012	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018	Dec. 12, 2013	Dec. 28, 2012
Convertible preferred stock, authorized														1,000,000
Convertible preferred stock, par value														$ 0.01
Warrants outstanding														$ 29,192,471	$ 22,599,177
Loan maturity date														Jun. 23, 2021
Proceeds from convertible preferred stock														$ 150,000	3,275,099
Fair value of warrant														4,700,000
Number of common stock value issued for consulting and investor services														$ 179,077	$ 398,600
Common stock, par value														$ 0.01	$ 0.01
Common stock, shares outstanding under the plan														15,790,603	11,289,336	8,131,555
Outstanding stock options, terminated														40,401	417,852
Total unrecognized compensation cost														$ 304,900
Number of shares issued, value
Adjusted beneficial conversion feature value for deemed dividend														1,756,311	$ 558,903
Accrued interest expense for loans														$ 4,136
Loan issue description														For our loan dated December 23, 2020, we are obligated to issue 100,000 warrants if the loan is not repaid before January 23, 2021 and an additional 10,000 shares of common stock if the loan is not repaid before February 23, 2021. We are also obligated to issue 10,000 shares of common stock and 200,000 warrants if the loan is not repaid before March 23, 2021. If the loan is not repaid on March 23, 2021, 10,000 shares of common stock will be issued every 31 days up to the loan's maturity date on June 23, 2021.
Issued For Services Rendered [Member]
Number of common stock shares issued for services														76,800	139,000
Number of common stock value issued for consulting and investor services														$ 179,077	$ 398,600
Conversion of Debt and Interest For Common Stock [Member]
Number of common stock shares issued, shares														871,309	126,200
Number of shares issued, value														$ 2,220,442	$ 356,510
Issued for Debt Extension [Member]
Number of common stock shares issued, shares														323,260	422,234
Number of shares issued, value														$ 629,809	$ 649,018
Shares with Fair Value [Member]
Number of common stock shares issued, shares														66,500
Number of shares issued, value														$ 127,855
Number of shares issued to settle an accrued liability														158,700
Issued in Conjunction with Signing of New Convertible Loans [Member]
Number of common stock shares issued, shares														214,419	80,237
Number of shares issued, value															$ 239,875
Unvested Stock-Based Awards [Member]
Total unrecognized compensation cost														$ 304,900	$ 761,770
Unvested stock options weighted average period														1 year 7 months 2 days	2 years 4 months 13 days
Aggregate intrinsic value of options outstanding and exercisable														$ 1,240,469	$ 136,683
Closing stock price														$ 2.12	$ 1.25
Board of Directors [Member]
Outstanding stock options, terminated		380,630
Compensation cost															$ 73,355	$ 759,469
Officers, Employees and Board [Member]
Outstanding stock options, terminated		1,014,240
Accredited Investor [Member]
Number of restricted stock issued														1,618,704	865,438
Number of restricted stock issued during period, value														$ 3,671,311	$ 1,849,103
Minimum [Member] \| Board of Directors [Member]
New stock options, exercise price		$ 0.69
Maximum [Member] \| Board of Directors [Member]
New stock options, exercise price		$ 3.40
Series D Registered Direct Offering [Member]
Warrant to purchase shares of common stock			39,778
Warrant exercise price per share			$ 8.40
Proceeds from exercises of warrants			$ 140,214
Number of warrants exercised			19,889
Fair value of warrant			$ 186,802
2013 Equity Incentive Plan [Member]
Common stock reserved for stock option plan																	3,000,000
Other Plans [Member]
Common stock, shares outstanding under the plan														1,355,901
Not Repaid Before January 23,2021, and February 23, 2021 [Member]
Warrants issued	10,000
Number of common stock shares issued, shares	10,000
Not Repaid Before March 23,2021 [Member]
Warrants issued	200,000
Number of common stock shares issued, shares	10,000
Not Repaid On March 23,2021 [Member]
Number of common stock shares issued, shares	10,000
Series D Warrants [Member]
Warrant exercise price per share														$ 24.30
Investor Warrants [Member]
Warrant to purchase shares of common stock														60,000	1,455,600
Fair value of warrant														$ 69,580	$ 2,307,909
Broker Warrants [Member]
Warrant to purchase shares of common stock															145,560
Preferred Stock [Member]
Convertible preferred stock, authorized														1,000,000
Convertible preferred stock, par value														$ 0.01
Convertible preferred stock, shares issued														1,000,000
Series A Junior Participating Preferred Stock [Member]
Convertible preferred stock, authorized														20,000
Convertible preferred stock, shares issued
Preferred stock, shares outstanding
Series A Convertible Preferred Stock [Member]
Convertible preferred stock, authorized														313,960
Convertible preferred stock, shares issued
Preferred stock, shares outstanding
Series B Convertible Preferred Stock [Member]
Convertible preferred stock, authorized														279,256
Convertible preferred stock, shares issued
Preferred stock, shares outstanding
Series C Convertible Preferred Stock [Member]
Convertible preferred stock, authorized														88,098
Convertible preferred stock, shares issued
Preferred stock, shares outstanding
Series D Convertible Preferred Stock [Member]
Convertible preferred stock, authorized														850	850
Convertible preferred stock, par value											$ 0.01			$ 0.01	$ 0.01
Convertible preferred stock, shares issued														300	300
Preferred stock, shares outstanding														300	300
Sale of stock											843
Purchase price per units sold											$ 1,000
Proceeds from direct offering											$ 843,000
Conversion of stock into shares											84
Warrants term											5 years
Warrant to purchase shares of common stock											21
Warrant exercise price per share											$ 24.30
Warrants exercisable date											May 11, 2012
Stock conversion price per share														$ 19.50
Convertible preferred stock, conversion percentage														300.00%
Average daily trading volume														50,000
Ownership percentage														50.00%
Amount to be paid at any uncertain situation value per share (subject to accrued but unpaid dividends)														$ 1,000
Series E Convertible Preferred Stock [Member]
Convertible preferred stock, authorized														500
Convertible preferred stock, shares issued
Preferred stock, shares outstanding
Series G Convertible Preferred Stock [Member]
Convertible preferred stock, authorized														240,000	240,000
Convertible preferred stock, par value									$ 0.01	$ 0.01				$ 0.01	$ 0.01
Convertible preferred stock, shares issued														80,570	80,570
Preferred stock, shares outstanding														80,570	80,570
Sale of stock									4,844	4,844
Purchase price per units sold									$ 150.00	$ 150.00
Proceeds from direct offering									$ 726,600	$ 726,600
Warrants term									3 years	3 years
Warrant to purchase shares of common stock									1	1
Warrant exercise price per share									$ 15.00	$ 15.00
Convertible preferred stock, conversion percentage														12.00%
Number of common stock shares issued, shares									1	1
Cumulative dividend rate percentage														4.00%
Percentage of shares purchased for investment														6.00%
Series G Convertible Preferred Stock [Member] \| Minimum [Member]
Purchase price per units sold														$ 22.50
Proceeds from direct offering														$ 2,500,000
Average daily trading volume														334
Investment amount														$ 100,000
Series G Convertible Preferred Stock [Member] \| Maximum [Member]
Investment amount														$ 250,000
Series H Convertible Preferred Stock [Member]
Convertible preferred stock, authorized								10,000						10,000	10,000			10,000
Convertible preferred stock, par value								$ 0.01						$ 0.01	$ 0.01
Convertible preferred stock, shares issued														10,000	10,000
Preferred stock, shares outstanding														10,000	10,000
Purchase price per units sold								$ 24.08
Conversion of stock into shares								4
Number of common shares exchanged								33,334
Common stock, par value								$ 0.01
Series H2 Convertible Preferred Stock [Member]
Convertible preferred stock, authorized				21										21	21
Convertible preferred stock, par value				$ 0.01										$ 0.01	$ 0.01
Convertible preferred stock, shares issued				21										21	21
Preferred stock, shares outstanding														21	21
Purchase price per units sold				$ 7.50
Conversion of stock into shares				3,334
Number of common shares exchanged				70,000
Common stock, par value				$ 0.01
Series J Convertible Preferred Stock [Member]
Convertible preferred stock, authorized														6,250	6,250
Convertible preferred stock, par value					$ 0.01	$ 0.01	$ 0.01							$ 0.01	$ 0.01
Convertible preferred stock, shares issued														3,458	3,458
Preferred stock, shares outstanding														3,458	3,458
Sale of stock					5,087.5	5,087.5	5,087.5
Purchase price per units sold					$ 400.00	$ 400.00	$ 400.00							$ 24.00
Proceeds from direct offering					$ 2,034,700	$ 2,034,700	$ 2,034,700
Conversion of stock into shares					34	34	34							34
Warrant to purchase shares of common stock					34	34	34
Warrant exercise price per share					$ 12.00	$ 12.00	$ 12.00
Average daily trading volume														1,667
Proceeds from convertible preferred stock														$ 250,000
Number of shares issued upon conversion						34	34
Series K Convertible Preferred Stock [Member]
Convertible preferred stock, authorized														15,000	15,000
Convertible preferred stock, par value														$ 0.01	$ 0.01
Convertible preferred stock, shares issued														6,880	6,880
Preferred stock, shares outstanding														6,880	6,880
Purchase price per units sold														$ 24.00
Proceeds from direct offering														$ 250,000
Conversion of stock into shares														34
Average daily trading volume														1,667
Value of shares invested in private placements														$ 100,000
Series AA Convertible Preferred Stock [Member]
Convertible preferred stock, authorized														10,000	10,000
Convertible preferred stock, par value														$ 0.01	$ 0.01
Convertible preferred stock, shares issued														8,043	7,939
Preferred stock, shares outstanding														8,043	7,939
Number of common stock shares issued, shares															81,767
Cumulative dividend rate percentage															8.00%
Number of preferred stock issued upon conversion															16
Number of shares issued upon conversion, value															$ 16,000
Number of shares issued, value															$ 205,100
Series AA Convertible Preferred Stock [Member] \| Securities Purchase Agreement [Member] \| Accredited Investors [Member]
Sale of stock														60	1,456
Warrant to purchase shares of common stock														60,000	1,455,600
Warrant exercise price per share														$ 3.50	$ 3.50
Number of preferred stock issued upon conversion														1,000	1,000
Common stock, par value														$ 0.01	$ 0.01
Sale of stock, amount														$ 150,000	$ 3,600,000
Series AA Convertible Preferred Stock [Member] \| Securities Purchase Agreement [Member] \| Placement Agent [Member]
Warrant to purchase shares of common stock															145,560
Fair value of warrant															$ 405,557
Cash fees															363,819
Series D Warrants [Member]
Warrant exercise price per share												$ 7.50	$ 12.00
Change in number of warrants												20,958	17,681
Warrants outstanding												$ 55,887	$ 34,930
Series AA Preferred Stock [Member]
Warrants term														5 years
Warrant to purchase shares of common stock														44,000
Warrant exercise price per share														$ 3.50
Fair value of warrant														$ 38,783
Number of common stock shares issued, shares														122,135
Cumulative dividend rate percentage														8.00%
Number of preferred stock issued upon conversion														44
Number of shares issued upon conversion, value														$ 110,000
Number of shares issued, value														299,709
Convertible Preferred Stock [Member]
Adjusted beneficial conversion feature value for deemed dividend														$ 61,180	$ 2,653,344