Pressure BioSciences, Inc. Annual report pursuant to Section 13 and 15(d)

Annual report pursuant to Section 13 and 15(d)

Stockholders' (Deficit) (Details Narrative)

Stockholders' (Deficit) (Details Narrative) - USD ($)																																	1 Months Ended		4 Months Ended	9 Months Ended	12 Months Ended
Stockholders' (Deficit) (Details Narrative) - USD ($)	Dec. 12, 2016	Nov. 16, 2016	Aug. 29, 2016	May 13, 2016	May 06, 2016	Sep. 25, 2015	Aug. 14, 2015	Aug. 13, 2015	Jul. 21, 2015	May 29, 2015	Apr. 17, 2015	Apr. 10, 2015	Mar. 31, 2015	Mar. 18, 2015	Feb. 25, 2015	Feb. 18, 2015	Jan. 14, 2015	Dec. 23, 2014	Nov. 12, 2014	Jun. 30, 2014	Feb. 28, 2014	Feb. 02, 2014	Jan. 30, 2014	Jan. 29, 2014	Dec. 12, 2013	May 20, 2013	Mar. 28, 2013	Feb. 06, 2013	Jan. 04, 2013	Nov. 15, 2012	Jul. 06, 2012	Nov. 11, 2011	Dec. 31, 2013	Apr. 30, 2012	Dec. 31, 2016	Sep. 30, 2016	Dec. 31, 2016	Dec. 31, 2015	Apr. 22, 2016	Nov. 29, 2015	Dec. 31, 2014	Nov. 10, 2014	Sep. 22, 2014	Jun. 04, 2014	Apr. 04, 2014	Jan. 31, 2014	Dec. 21, 2013	Dec. 04, 2013	Dec. 28, 2012
Convertible preferred stock, authorized																																			1,000,000		1,000,000	1,000,000
Convertible preferred stock, par value																																			$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued																																			1,000,000		1,000,000	1,000,000
Proceeds from warrants issued																																					$ 6,329,549
Adjustment to additional paid in capital related to the beneficial conversion feature																																					$ 20,721
Common stock, shares outstanding under the plan																																			31,728,945		31,728,945	34,798,914			22,588,451
Convertible debt amount																																										$ 75,000		$ 150,000				$ 223,000
Conversion of convertible debt				$ 117,837		$ 30,000		$ 40,000	$ 20,000	$ 35,000	$ 30,000	$ 35,000	$ 27,500	$ 22,500	$ 38,000	$ 25,000	$ 25,000																				$ 145,931	$ 58,919
Conversion of convertible debt, shares				420,849		120,000		160,000	80,000	140,000	120,000	140,000	110,000	90,000	140,741	100,000	100,000																					235,676
Number of common stock shares issued for services																																						1,755,091
Number of common stock value issued for consulting and investor services																																					332,696	$ 457,030
Interest expense																																					$ 4,501,186	$ 4,146,416
Cashless exercise common stock shares issued																																							22,996
Cashless exercise warrants issued																																							70,000
Common stock shares issued																																			30,999,839		30,999,839	23,004,898
Stock Issued During Period, Value, New Issues																																					$ 610,000
Warrents issued																																			$ 6,325,102		$ 6,325,102	$ 5,416,681
Common stock, par value																																			$ 0.01		$ 0.01	$ 0.01
Securities Exchange Agreement [Member] \| Everest Investments Holding [Member]
Aggregate number of units sold							601,500
Purchase price per units sold							$ 0.50
Number of restricted common stock purchased							1,000,000
Sale of stock value of shares received							$ 400,000
Investor [Member]
Number of common stock shares issued for services																																						1,755,091
Number of common stock value issued for consulting and investor services																																						$ 457,030
Warrents issued																																						$ 93,488
Lender [Member]
Aggregate number of units sold																																					40,000
Interest expense																																					$ 10,000
Lenders [Member]
Conversion of convertible debt																																				$ 41,200
Conversion of convertible debt, shares																																				100,049
2005 Equity Incentive [Member]
Common stock reserved for stock option plan																																			1,800,000		1,800,000
Common stock, shares outstanding under the plan																																			1,153,750		1,153,750
Common stock, shares available for future grant																																			586,250		586,250
2013 Equity Incentive Plan [Member]
Common stock reserved for stock option plan																									3,000,000
Common stock, shares outstanding under the plan																									2,047,500
Common stock, shares available for future grant																									952,500
2015 Equity Incentive Plan [Member]
Common stock reserved for stock option plan																																								5,000,000
Common stock, shares outstanding under the plan																																								2,068,000
Common stock, shares available for future grant																																								2,932,000
Weighted average grant date fair value of options issued																																					$ 0.27
Unrecognized compensation cost																																					$ 369,224
Compensation cost reorganization period																																					1 year 9 months 22 days
Restricted Common Stock [Member]
Number of common stock shares issued for services																																					755,000
Number of common stock value issued for consulting and investor services																																					$ 332,696
Extension One [Member]
Debenture fee																																			$ 13,000		13,000
Extension Two [Member]
Debenture fee																																			13,000		13,000
Extension Three [Member]
Debenture fee																																			10,000		10,000
Extension Four [Member]
Debenture fee																																			$ 8,000		$ 8,000
Five Tranches [Member]
Stock issuance price per share																																			$ 0.40		$ 0.40
Stock Issued During Period, Shares, New Issues																																			1,525,000
Stock Issued During Period, Value, New Issues																																			$ 610,000
Common stock, par value																																			$ 0.01		0.01
Five Tranches [Member] \| Investor [Member]
Issuance of warrants to purchase of common stock shares																																			1,525,000
Warrants exercise price per share																																			$ 0.50		$ 0.50
Warrent term																																			5 years
Payments of stock issuance costs																																			$ 79,035
Series D Convertible Preferred Stock [Member]
Proceeds from convertible preferred stock																																					$ 559,275
Additional paid in capital and accumulated deficit																																					530,140
Adjustment to additional paid in capital related to the beneficial conversion feature																																					$ 530,140
Convertible preferred stock, conversion percentage																																					300.00%
Subsequent financing pro-rata basis percentage																																					50.00%
Series D Warrant [Member]
Warrants exercise price per share																																	$ 0.25	$ 0.40	$ 0.81		$ 0.81
Change in number of warrants																																	628,733	530,406
Number of warrants issued during period																																	1,676,608	1,047,875
Series D Warrant [Member] \| Merger Or Consolidation [Member]
Percentage of stock acquired																																					50.00%
Series G Warrant [Member]
Warrants exercise price per share																																			0.50		$ 0.50
Warrants expiration date																																					Jul. 06, 2015
Change in exercise price of warrants																																			0.60		$ 0.60
Series J Warrant [Member]
Warrants exercise price per share																																			$ 0.40		$ 0.40
Series J Warrant [Member] \| Minimum [Member]
Change in number of warrants																																					5,000,000
Series K Warrant [Member]
Proceeds from direct offering																						$ 5,000,000
Warrants exercise price per share																			$ 0.3125	$ 0.375	$ 0.425			$ 0.3125																							$ 0.3125
Warrant Derivative Liability [Member]
Proceeds from direct offering																																					$ 283,725
Weighted average grant date fair value of options issued																																					$ 0.40	$ 0.40
Aggregate warrant to lenders to purchase commno stock shares																																					8,767,857	2,517,052
Aggregate warrant to placement agent to purchase common stock shares																																					1,689,286	412,500
Warrant expiring term																																					5 years	5 years
Incremental value of warrant extension																																						$ 69,627
Convertible Debt [Member] \| Lenders [Member]
Conversion of convertible debt, shares																																				297,500
Series A Junior Participating Preferred Stock [Member]
Number of stock designated																																			20,000		20,000
Series A Convertible Preferred Stock [Member]
Number of stock designated																																			313,960		313,960
Series B Convertible Preferred Stock [Member]
Number of stock designated																																			279,256		279,256
Series C Convertible Preferred Stock [Member]
Number of stock designated																																			88,098		88,098
Series D Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																																			850		850	850
Convertible preferred stock, par value																																$ 0.01			$ .01		$ .01	$ .01
Convertible preferred stock, shares issued																																			300		300	300
Number of stock designated																																			850		850
Preferred stock shares outstanding																																			300		300	300
Aggregate number of units sold																																843
Purchase price per units sold																																$ 1,000
Proceeds from direct offering																																$ 843,000
Issuance of warrants to purchase of common stock shares																																614
Warrants exercise price per share																																$ 0.81
Amount to be paid at any uncertain situation value per share (subject to accrued but unpaid dividends)																																			$ 1,000		$ 1,000
Preferred stock value issued																																			$ 3		$ 3	$ 3
Change in exercise price of warrants																																			$ 0.65		$ 0.65
Series D Convertible Preferred Stock [Member] \| Merger Or Consolidation [Member]
Proceeds from convertible preferred stock																																					$ 50,000
Percentage of stock acquired																																					50.00%
Series D Convertible Preferred Stock [Member] \| Series D Warrant [Member]
Proceeds from warrants issued																																					$ 283,725
Series E Convertible Preferred Stock [Member]
Number of stock designated																																			500		500
Series G Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																																			240,000		240,000	240,000
Convertible preferred stock, par value																															$ 0.01				$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued																																			86,570		86,570	86,570
Number of stock designated																																			240,000		240,000
Preferred stock shares outstanding																																			86,570		86,570	86,570
Aggregate number of units sold																														145,320	145,320
Purchase price per units sold																														$ 5.00	$ 5.00
Proceeds from direct offering																														$ 726,600	$ 726,600
Issuance of warrants to purchase of common stock shares																																					5
Warrants exercise price per share																															$ 0.50				$ 0.50		$ 0.50
Convertible preferred stock, conversion percentage																																					12.00%
Percentage of shares purchased for investment																																					6.00%
Value of shares invested in private placements																																					$ 726,600
Cumulative dividend rate percentage																																					4.00%
Preferred stock value issued																																			$ 866		$ 866	$ 866
Stock issuance price per share																																			$ 0.75		$ 0.75
Warrant expiring term																															3 years
Series G Convertible Preferred Stock [Member] \| Minimum [Member]
Proceeds from direct offering																																					$ 2,500,000
Value of shares invested in private placements																																					250,000
Preferred stock value issued																																			$ 100,000		$ 100,000
Average daily trading volume																																					10,000
Series G Convertible Preferred Stock [Member] \| Maximum [Member]
Preferred stock value issued																																			$ 250,000		$ 250,000
Series H Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																																			10,000		10,000	10,000											10,000
Convertible preferred stock, par value																													$ 0.01						$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued																																			10,000		10,000	10,000
Number of stock designated																																			10,000		10,000
Preferred stock shares outstanding																																			10,000		10,000	10,000
Purchase price per units sold																													$ 0.8025
Issuance of warrants to purchase of common stock shares																													100
Preferred stock value issued																																			$ 100		$ 100	$ 100
Series H2 Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																																			21		21	21
Convertible preferred stock, par value																		$ 0.01																	$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued																		21																	21		21	21
Number of stock designated																																			21		21
Preferred stock shares outstanding																																			21		21	21
Purchase price per units sold																		$ 0.25
Issuance of warrants to purchase of common stock shares																		100,000
Preferred stock value issued
Series J Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																																			6,250		6,250	6,250
Convertible preferred stock, par value																										$ 0.01	$ 0.01	$ 0.01							$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued																																			3,521		3,521	3,546
Number of stock designated																																			6,250		6,250
Preferred stock shares outstanding																																			3,521		3,521	3,546
Aggregate number of units sold																										5,087.5	5,087.5	5,087.5
Purchase price per units sold																										$ 400.00	$ 400.00	$ 400.00
Proceeds from direct offering																										$ 2,034,700	$ 2,034,700	$ 2,034,700									$ 2,500,000
Convertible preferred stock, shares outstanding			25
Issuance of warrants to purchase of common stock shares																																					1,000
Warrants exercise price per share																																			$ 0.40		$ 0.40
Convertible preferred stock, conversion percentage																																					4.00%
Percentage of stock acquired																																					6.00%
Value of shares invested in private placements																												250,000									$ 2,034,700
Preferred stock value issued																												$ 250,000							$ 35		$ 35	$ 36
Stock issuance price per share																																			$ 0.80		$ 0.80
Warrants expiration term																																					P3Y
Common stock shares issued			1,112
Accrued dividend			$ 442
Convertible preferred stock common stock shares issued			25,000
Series J Convertible Preferred Stock [Member] \| Minimum [Member]
Value of shares invested in private placements																																					$ 2,500,000
Stock issuance price per share																																			$ 0.80		$ 0.80
Average daily trading volume																																					50,000
Series K Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																																			15,000		15,000	15,000
Convertible preferred stock, par value																			$ 0.01	$ 0.01	$ 0.01			$ 0.01											$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued																			1,000	1,000	1,000			1,000											6,816		6,816	11,416					64,000
Number of stock designated																																			15,000		15,000
Preferred stock shares outstanding					4,600																														6,816		6,816	11,416
Aggregate number of units sold																			1,052	734	1,854			4,875	4,000
Purchase price per units sold																			$ 250.00	$ 300.00	$ 340.00			$ 250.00	$ 250.00
Proceeds from direct offering																			$ 263,000	$ 220,000	$ 630,360		$ 1,500,000	$ 1,218,750	$ 1,000,000												$ 100,000
Issuance of warrants to purchase of common stock shares																			500	500	500			500													1,000
Warrants exercise price per share																			$ 0.3125	$ 0.375	$ 0.425														$ 0.3125		$ 0.3125
Proceeds from warrants issued																																					$ 271,422
Proceeds from convertible preferred stock																																					685,245
Adjustment to additional paid in capital related to the beneficial conversion feature																																					$ 1,495,415
Convertible preferred stock, conversion percentage																																					4.00%
Percentage of stock acquired																																					6.00%
Number of warrants issued during period																																					500
Value of shares invested in private placements																			$ 3,332,110																		$ 1,000,000
Cash received in private placement																			2,511,404																		572,044
Conversion of outstanding indebtedness and accrued board of directors' fees																			$ 820,706																$ 427,956		427,956
Preferred stock value issued																																			$ 68		$ 68	$ 114
Stock issuance price per share																																			$ 0.80		$ 0.80
Average daily trading volume																																					50,000
Warrants expiration date																			Nov. 12, 2017	Jun. 30, 2017	Feb. 28, 2017			Jan. 29, 2017
Fee incurred with private placement																																					$ 43,334
Increase in subscription amount																					$ 3,500,000			$ 718,750
Common stock shares issued					247,435
Accrued dividend					$ 63,413
Series K Convertible Preferred Stock [Member] \| Tranche Two [Member]
Proceeds from direct offering																								$ 1,500,000
Increase in subscription amount																																														$ 1,218,750
Series K Convertible Preferred Stock [Member] \| Tranche Third [Member]
Proceeds from direct offering																					1,500,000
Increase in subscription amount																					$ 630,360
Series K Convertible Preferred Stock [Member] \| Fourth Tranche [Member]
Proceeds from direct offering																				$ 1,500,000
Increase in subscription amount																				$ 220,000
Series K Convertible Preferred Stock [Member] \| Fifth Tranche [Member]
Proceeds from direct offering																			$ 1,500,000
Increase in subscription amount																			$ 263,000
Series K Convertible Preferred Stock [Member] \| Initial Tranche [Member]
Increase in subscription amount																									$ 1,000,000
Series K Convertible Preferred Stock [Member] \| Minimum [Member]
Proceeds from direct offering	$ 2,500,000
Increase in subscription amount																																													$ 4,500,000
Series K Convertible Preferred Stock [Member] \| Maximum [Member]
Increase in subscription amount																																													$ 1,000,000
Restricted Common Stock [Member] \| Investor [Member]
Number of common stock shares issued for services		330,000
Number of common stock value issued for consulting and investor services		$ 84,735
Stock Issued During Period, Shares, New Issues																																						300,000