Pressure BioSciences, Inc. Annual report pursuant to Section 13 and 15(d)

Annual report pursuant to Section 13 and 15(d)

Stockholders' (Deficit) (Details Narrative)

Stockholders' (Deficit) (Details Narrative) - USD ($)																														1 Months Ended				12 Months Ended
Stockholders' (Deficit) (Details Narrative) - USD ($)	Dec. 12, 2015	Oct. 26, 2015	Sep. 25, 2015	Aug. 14, 2015	Aug. 13, 2015	Jul. 21, 2015	May. 29, 2015	Apr. 17, 2015	Apr. 10, 2015	Mar. 31, 2015	Mar. 18, 2015	Feb. 25, 2015	Feb. 18, 2015	Jan. 12, 2015	Dec. 23, 2014	Dec. 12, 2014	Nov. 11, 2014	Nov. 09, 2014	Jun. 30, 2014	Feb. 28, 2014	Feb. 02, 2014	Jan. 30, 2014	Jan. 28, 2014	May. 20, 2013	Mar. 28, 2013	Feb. 06, 2013	Jan. 04, 2013	Nov. 15, 2012	Jul. 06, 2012	Dec. 31, 2015	Dec. 31, 2013	Apr. 30, 2012	Nov. 30, 2011	Dec. 31, 2015	Dec. 31, 2014	Jan. 15, 2015	Nov. 12, 2014	Sep. 22, 2014	Jun. 04, 2014	Apr. 04, 2014	Jan. 31, 2014	Dec. 21, 2013	Dec. 12, 2013	Dec. 04, 2013	Dec. 28, 2012
Convertible preferred stock, authorized																														1,000,000				1,000,000
Convertible preferred stock, par value																														$ 0.01				$ 0.01
Convertible preferred stock, shares issued																														1,000,000				1,000,000
Convertible preferred stock, shares outstanding																	40,000
Proceeds from convertible preferred stock																																			$ 1,939,360
Common stock, shares outstanding under the plan																														34,863,199	16,784,035			34,863,199	22,588,451
Convertible debt amount																	$ 75,000																						$ 150,000					$ 223,000
Conversion of convertible debt			$ 30,000		$ 40,000	$ 20,000	$ 35,000	$ 30,000	$ 35,000	$ 27,500	$ 22,500	$ 38,000	$ 25,000	$ 25,000																$ 58,919
Conversion of convertible debt, shares			120,000		160,000	80,000	140,000	120,000	140,000	110,000	90,000	140,741	100,000	100,000																235,676
Debenture fee							$ 8,000		$ 10,000			$ 13,000																								$ 13,000
Number of common stock shares issued for services																																		1,755,091
Number of common stock value issued for consulting and investor services																																		$ 457,030	$ 214,192
Number of restricted common stock purchased		200,000
Interest expense																		$ 10,000																4,146,416	1,303,129
Conversion option liability																														$ 3,940,791				3,940,791
Accrued dividends																																		$ (23,194)	$ (143,771)
Everest Investments Holding [Member]
Aggregate number of units sold				601,500
Sale of stock value of shares received				$ 400,000
2005 Equity Incentive [Member]
Common stock reserved for stock option plan																														1,800,000				1,800,000
Common stock, shares outstanding under the plan																														1,395,750				1,395,750
Common stock, shares available for future grant																														344,250				344,250
2013 Equity Incentive Plan [Member]
Common stock reserved for stock option plan																																											3,000,000
Common stock, shares outstanding under the plan																																											2,107,500
Common stock, shares available for future grant																																											892,500
2015 Equity Incentive Plan [Member]
Common stock reserved for stock option plan																														5,000,000				5,000,000
Common stock, shares outstanding under the plan																														2,068,000				2,068,000
Common stock, shares available for future grant																														2,932,000				2,932,000
Weighted average grant date fair value of options issued																																		$ 0.27
Unrecognized compensation cost																																		$ 740,117
Compensation cost reorganization period																																		2 years 5 months 12 days
Restricted Stock Units [Member] \| Everest Investments Holding [Member]
Stock issuance price per share				$ 0.50
Number of restricted common stock purchased				1,000,000
CommonStockMember [Member]
Conversion of convertible debt
Conversion of convertible debt, shares
Number of common stock shares issued for services																																		1,755,091	588,830
Number of common stock value issued for consulting and investor services																																		$ 17,551	$ 5,888
Accrued dividends
Series D Warrant [Member]
Warrants exercise price per share																															$ 0.25	$ 0.40
Change in number of warrants																															628,733	530,406
Number of Warrants issued during period																															1,676,608	1,047,875
Increase decrease in warrants value																																		$ 173,526
Series D Warrant [Member] \| Merger Or Consolidation [Member]
Percentage of stock acquired																																		50.00%
Series G Warrant [Member]
Warrants exercise price per share																														$ 0.50				$ 0.50
Number of Warrants issued during period																																		1,495,022
Warrants expiration date																																		Jul. 06, 2015
Change in exercise price of warrants																														0.60				$ 0.60
Series J Warrant [Member]
Warrants exercise price per share																														$ 0.40				$ 0.40
Series J Warrant [Member] \| Minimum [Member]
Change in number of warrants																																		5,000,000
Series K Warrant [Member]
Proceeds from direct offering																					$ 5,000,000
Warrants exercise price per share																			$ 0.375	$ 0.425																	$ 0.3125				$ 0.3125	$ 0.3125
Warrant Derivative Liability [Member]
Proceeds from direct offering																																		$ 283,725	$ 149,165
Issuance of warrants to purchase of common stock shares																																			596,658
Warrants exercise price per share																																			$ 0.25
Aggregate warrant to lenders to purchase commno stock shares																																		8,767,857
Aggregate warrant to placement agent to purchase common stock shares																																		1,689,286
Warrant expiring term																																		5 years
Incremental value of warrant extension																																		$ 69,627
Warrant expense recorded																																		$ 93,488
Series A Junior Participating Preferred Stock [Member]
Number of stock designated																														20,000				20,000
Series A Junior Participating Preferred Stock [Member] \| Shareholders Purchase Rights Plan [Member]
Purchase price per units sold																														$ 45.00				$ 45.00
Percentage of stock acquired																																		50.00%
Conversion price per share																														$ 0.001				$ 0.001
Common stock acquires beneficial ownership description																																		Subject to certain limited exceptions, if a person or group acquires beneficial ownership of 15% or more of our outstanding common stock or if a current 15% beneficial owner acquires additional shares of common stock, each holder of a Right (other than the 15% holder whose Rights become void once such holder reaches the 15% threshold) will thereafter have a right to purchase, upon payment of the purchase price of the Right, that number of shares of our common stock which at the time of such transaction will have a market value equal to two times the purchase price of the Right In the event that, at any time after a person or group acquires 15% or more of our common stock, we are acquired in a merger or other business combination transaction or 50% or more of its consolidated assets or earning power are sold, each holder of a Right will thereafter have the right to purchase, upon payment of the purchase price of the Right, that number of shares of common stock of the acquiring company which at the time of such transaction will have a market value of two times the purchase price of the Right.
Beneficial ownership percentage																																		15.00%
Series A Junior Participating Preferred Stock [Member] \| Shareholders Purchase Rights Plan [Member] \| CommonStockMember [Member]
Percentage of stock acquired																																		15.00%
Series A Convertible Preferred Stock [Member]
Number of stock designated																														313,960				313,960
Series B Convertible Preferred Stock [Member]
Number of stock designated																														279,256				279,256
Series C Convertible Preferred Stock [Member]
Number of stock designated																														88,098				88,098
Series D Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																														850				850	850
Convertible preferred stock, par value																														$ 0.01				$ 0.01	$ 0.01
Convertible preferred stock, shares issued																														300				300	300
Number of stock designated																														850				850
Preferred stock shares outstanding																														300				300	300
Aggregate number of units sold																																	843
Purchase price per units sold																																	$ 1,000
Proceeds from direct offering																																	$ 843,000
Convertible preferred stock, shares outstanding																														1,538.46			1,538.46	1,538.46
Issuance of warrants to purchase of common stock shares																																	614
Warrants exercise price per share																																	$ 0.81
Proceeds from convertible preferred stock																																		$ 559,275
Additional paid in capital and accumulated deficit																																		530,140
Adjustment to additional paid in capital related to the beneficial conversion feature																																		530,140
Amount to be paid at any uncertain situation value per share (subject to accrued but unpaid dividends)																														$ 1,000				$ 1,000
Convertible preferred stock, conversion percentage																																		300.00%
Subsequent financing pro-rata basis percentage																																		50.00%
Preferred stock value issued																														$ 3				$ 3	$ 3
Series D Convertible Preferred Stock [Member] \| Merger Or Consolidation [Member]
Proceeds from convertible preferred stock																																		$ 50,000
Percentage of stock acquired																																		50.00%
Series D Convertible Preferred Stock [Member] \| Series D Warrant [Member]
Fee paid to investment banker																																		$ 67,000
Proceeds from warrants issued																																		$ 283,725
Series E Convertible Preferred Stock [Member]
Number of stock designated																														500				500
Series G Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																														240,000				240,000	240,000
Convertible preferred stock, par value																														$ 0.01				$ 0.01	$ 0.01
Convertible preferred stock, shares issued																														86,570				86,570	86,570
Number of stock designated																														240,000				240,000
Preferred stock shares outstanding																														86,570				86,570	86,570
Aggregate number of units sold																												145,320	145,320
Purchase price per units sold																												$ 5.00	$ 5.00
Proceeds from direct offering																												$ 726,600	$ 726,600
Convertible preferred stock, shares outstanding																														10				10
Issuance of warrants to purchase of common stock shares																																		5
Warrants exercise price per share																														$ 0.50				$ 0.50
Convertible preferred stock, conversion percentage																																		12.00%
Percentage of shares purchased for investment																																		6.00%
Value of shares invested in private placements																																		$ 726,600
Cash received in private placement																																		31,100
Conversion of outstanding indebtedness and accrued board of directors' fees																														$ 695,500				$ 695,500
Cumulative dividend rate percentage																																		4.00%
Preferred stock value issued																														$ 866				$ 866	$ 866
Stock issuance price per share																														$ 0.75				$ 0.75
Series G Convertible Preferred Stock [Member] \| Minimum [Member]
Proceeds from direct offering																																		$ 2,500,000
Value of shares invested in private placements																																		250,000
Preferred stock value issued																														$ 100,000				$ 100,000
Average daily trading volume																																		10,000
Series G Convertible Preferred Stock [Member] \| Maximum [Member]
Preferred stock value issued																														$ 250,000				$ 250,000
Series H Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																														10,000				10,000	10,000										10,000
Convertible preferred stock, par value																											$ 0.01			$ 0.01				$ 0.01	$ 0.01
Convertible preferred stock, shares issued																														10,000				10,000	10,000
Number of stock designated																														10,000				10,000
Preferred stock shares outstanding																														10,000				10,000	10,000
Purchase price per units sold																											$ 0.8025
Convertible preferred stock, shares outstanding																											1,000,000			10,000				10,000
Issuance of warrants to purchase of common stock shares																											100
Preferred stock value issued																														$ 100				$ 100	$ 100
Series H2 Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																														21				21	21
Convertible preferred stock, par value															$ 0.01															$ 0.01				$ 0.01	$ 0.01
Convertible preferred stock, shares issued															21															21				21	21
Number of stock designated																														21				21
Preferred stock shares outstanding																														21				21	21
Purchase price per units sold															$ 0.25
Convertible preferred stock, shares outstanding															2,100,000															21				21
Issuance of warrants to purchase of common stock shares															100,000
Preferred stock value issued
Series J Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																														6,250				6,250	6,250
Convertible preferred stock, par value																														$ 0.01				$ 0.01	$ 0.01
Convertible preferred stock, shares issued																														3,546				3,546	3,546
Number of stock designated																														6,250				6,250
Preferred stock shares outstanding																														3,546				3,546	3,546
Aggregate number of units sold																								5,087	5,087.5	5,087.5
Purchase price per units sold																								$ 400.00	$ 400.00	$ 400.00
Proceeds from direct offering																								$ 2,034,700	$ 2,034,700	$ 2,034,700								$ 2,500,000
Issuance of warrants to purchase of common stock shares																																		1,000
Warrants exercise price per share																														$ 0.40				$ 0.40
Proceeds from warrants issued																																		$ 885,309
Additional paid in capital and accumulated deficit																																		651,182
Adjustment to additional paid in capital related to the beneficial conversion feature																																		$ 651,182
Convertible preferred stock, conversion percentage																																		4.00%
Percentage of stock acquired																																		6.00%
Value of shares invested in private placements																																		$ 2,034,700
Cash received in private placement																																		921,000
Conversion of outstanding indebtedness and accrued board of directors' fees																														$ 1,113,700				1,113,700
Preferred stock value issued																														$ 36				$ 36	$ 36
Stock issuance price per share																														$ 0.80				$ 0.80
Warrants expiration term																																		P3Y
Legal fees																																		$ 24,405
Series J Convertible Preferred Stock [Member] \| Minimum [Member]
Value of shares invested in private placements																																		$ 250,000
Stock issuance price per share																														$ 0.80				$ 0.80
Series K Convertible Preferred Stock [Member]
Convertible preferred stock, authorized																														15,000				15,000	15,000
Convertible preferred stock, par value																	$ 0.01		$ 0.01	$ 0.01										$ 0.01				$ 0.01	$ 0.01
Convertible preferred stock, shares issued																	1,000		1,000	1,000										11,416				11,416	11,416			64,000
Number of stock designated																														15,000				15,000
Preferred stock shares outstanding																														11,416				11,416	11,416
Aggregate number of units sold	4,000																1,052		734	1,854			4,875
Purchase price per units sold	$ 250.00																$ 250.00		$ 300.00	$ 340.00			$ 250.00
Proceeds from direct offering	$ 1,000,000																$ 263,000		$ 220,000	$ 630,360		$ 1,500,000	$ 1,218,750											$ 100,000
Convertible preferred stock, shares outstanding																														11,416				11,416				64
Issuance of warrants to purchase of common stock shares																	500		500	500			500											1,000
Warrants exercise price per share																	$ 0.3125		$ 0.425	$ 0.425										$ 0.3125				$ 0.3125
Proceeds from warrants issued																																		$ 271,422
Additional paid in capital and accumulated deficit																																		351,421
Adjustment to additional paid in capital related to the beneficial conversion feature																																		$ 351,421
Convertible preferred stock, conversion percentage																																		4.00%
Percentage of stock acquired																																		6.00%
Number of Warrants issued during period																																		500
Value of shares invested in private placements																	$ 3,332,110																	$ 1,000,000
Cash received in private placement																	2,511,404																	572,044
Conversion of outstanding indebtedness and accrued board of directors' fees																	$ 820,706													$ 427,956				427,956
Preferred stock value issued																														$ 114				$ 114	$ 114
Stock issuance price per share																														$ 0.80				$ 0.80
Average daily trading volume																																		50,000
Warrants expiration date																	Nov. 12, 2017		Jun. 30, 2017	Feb. 28, 2017			Jan. 29, 2017
Fee incurred with private placement																																		$ 43,334
Increase in subscription amount																				$ 3,500,000			$ 718,750
Accrued dividends	23,194															$ 143,771
Series K Convertible Preferred Stock [Member] \| Tranche Two [Member]
Proceeds from direct offering																							$ 1,500,000
Increase in subscription amount																																									$ 1,218,750
Series K Convertible Preferred Stock [Member] \| Tranche Third [Member]
Proceeds from direct offering																				1,500,000
Increase in subscription amount																				$ 630,360
Series K Convertible Preferred Stock [Member] \| Fourth Tranche [Member]
Proceeds from direct offering																			$ 1,500,000
Increase in subscription amount																			$ 220,000
Series K Convertible Preferred Stock [Member] \| Fifth Tranche [Member]
Proceeds from direct offering																	$ 1,500,000
Increase in subscription amount																																					$ 263,000
Series K Convertible Preferred Stock [Member] \| Initial Tranche [Member]
Increase in subscription amount																																											$ 1,000,000
Series K Convertible Preferred Stock [Member] \| Minimum [Member]
Proceeds from direct offering	$ 2,500,000
Increase in subscription amount																																								$ 4,500,000
Series K Convertible Preferred Stock [Member] \| Maximum [Member]
Increase in subscription amount																																								$ 1,000,000