Pressure BioSciences, Inc. Annual report pursuant to Section 13 and 15(d)

Annual report pursuant to Section 13 and 15(d)

Stockholders' (Deficit) (Details Narrative)

Stockholders' (Deficit) (Details Narrative) - USD ($)																				1 Months Ended		3 Months Ended	9 Months Ended	12 Months Ended
Stockholders' (Deficit) (Details Narrative) - USD ($)	Dec. 31, 2019	Nov. 05, 2019	Dec. 31, 2018	Nov. 05, 2018	Jul. 18, 2018	Jun. 11, 2018	Jun. 02, 2018	May 14, 2018	May 02, 2018	May 02, 2018	May 10, 2017	Dec. 23, 2014	May 30, 2013	Mar. 28, 2013	Feb. 06, 2013	Jan. 04, 2013	Nov. 05, 2012	Jul. 06, 2012	Nov. 11, 2011	Dec. 31, 2013	Apr. 30, 2012	Dec. 31, 2018	Sep. 30, 2018	Dec. 31, 2019	Dec. 31, 2018	Mar. 12, 2018	Dec. 31, 2017	Nov. 29, 2015	Dec. 12, 2013	Dec. 28, 2012
Proceeds from convertible preferred stock																								$ 3,275,099	$ 2,824,664
Warrants outstanding	$ 22,599,177		$ 19,807,247																			$ 19,807,247		$ 22,599,177	$ 19,807,247
Number of common stock shares issued for services
Number of common stock value issued for consulting and investor services																								$ 398,600	$ 238,120
Common stock, par value	$ 0.01		$ 0.01																			$ 0.01		$ 0.01	$ 0.01
Debt converted principal amount																									$ 12,688,635
Debt conversion price per share	$ 7.50																							$ 7.50
Common stock, shares outstanding under the plan	8,131,555		8,131,555																			8,131,555		8,131,555	8,131,555		1,147,234
Outstanding stock options, terminated																								417,852	455,092
New stock options, exercise price	$ 3.40																							$ 3.40
Stock options issued																								3,600,634	7,452,416
Total unrecognized compensation cost	$ 761,770																							$ 761,770
Number of shares issued, value
Adjusted beneficial conversion feature value for deemed dividend																								$ 558,903
Issued For Services Rendered [Member]
Number of common stock shares issued for services																								139,000
Number of common stock value issued for consulting and investor services																								$ 398,600
Conversion of Debt and Interest For Common Stock [Member]
Number of common stock shares issued, shares																								126,200
Number of shares issued, value																								$ 356,510
Issued for Debt Extension [Member]
Number of common stock shares issued, shares																								422,234
Number of shares issued, value																								$ 649,018
Issued in Conjunction with Signing of New Convertible Loans [Member]
Number of common stock shares issued, shares																								80,237
Number of shares issued, value																								$ 239,875
Unvested Stock-Based Awards [Member]
Total unrecognized compensation cost	801,885		$ 761,770																			$ 761,770		$ 801,885	$ 761,770
Unvested stock options weighted average period																								2 years 4 months 13 days	1 year 1 month 24 days
Aggregate intrinsic value of options outstanding and exercisable	$ 136,683		$ 0																			$ 0		$ 136,683	$ 0
Closing stock price	$ 1.25		$ 2.25																			$ 2.25		$ 1.25	$ 2.25
Board of Directors [Member]
Outstanding stock options, terminated	380,630
Compensation cost																								$ 73,355	$ 759,469
Current Officers, Employees and Board Members [Member]
New stock options, exercise price					$ 3.40
Board Members [Member]
Stock options, vesting period					12 months
Debt maturity date					Jul. 18, 2028
Current Officers and Employees [Member]
Stock options, vesting period					36 months
Officers, Employees and Board [Member]
Outstanding stock options, terminated	1,014,240
New stock options, exercise price				$ 3.40
Stock options issued		25,000
Officers, Employees and Board [Member] \| Black Scholes Method [Member]
New stock options, exercise price				$ 3.07
Accredited Investor [Member]
Number of restricted stock issued																								865,438
Number of restricted stock issued during period, value																								$ 1,849,103
Letter Agreement [Member]
Debt converted principal amount						$ 742,134
Debt converted of shares						296.80
Terminated and Reissues [Member] \| Current Officers, Employees and Board Members [Member]
Outstanding stock options, terminated					244,467
Minimum [Member] \| Board of Directors [Member]
New stock options, exercise price	$ 0.69																							$ 0.69
Maximum [Member] \| Board of Directors [Member]
New stock options, exercise price	$ 3.40																							$ 3.40
Series D Registered Direct Offering [Member]
Warrant to purchase shares of common stock											39,778
Warrant exercise price per share											$ 8.40
Proceeds from warrants issued											$ 140,214
Proceeds from exercises of warrants											$ 140,214
Number of warrants exercised											19,889
Fair value of warrant											$ 186,802
Number of common stock shares issued, shares											19,889
2013 Equity Incentive Plan [Member]
Common stock reserved for stock option plan																													3,000,000
Other Plans [Member]
Common stock, shares outstanding under the plan	1,396,302																							1,396,302
Other Plans [Member] \| Terminated and Reissues [Member]
Outstanding stock options, terminated			32,605
Stock options issued			32,605
2015 Nonqualified Stock Option Plan [Member]
Stock options issued			49,333	203,734
Unamortized expense				$ 108,400
2015 Nonqualified Stock Option Plan [Member] \| Board of Directors [Member]
Common stock reserved for stock option plan																												5,000,000
Number of shares awarded																												2,917,519
2015 Nonqualified Stock Option Plan [Member] \| Terminated and Reissues [Member]
Outstanding stock options, terminated			129,937
Stock options issued			15,964
Reissuance of stock options			129,937
2013 Equity Incentive Plan [Member]
Stock options issued			51,934
2013 Equity Incentive Plan [Member] \| Terminated and Reissues [Member]
Outstanding stock options, terminated			81,925
Stock options issued			16,641
Reissuance of stock options			81,925
Restricted Common Stock [Member] \| Services Rendered [Member]
Number of restricted stock issued																									68,000
Number of restricted stock issued during period, value																									$ 238,120
Restricted Common Stock [Member] \| Accredited Investors [Member]
Number of restricted stock issued																									341,324
Number of restricted stock issued during period, value																									$ 1,005,941
Restricted Common Stock [Member] \| Existing Holders [Member]
Number of restricted stock issued																									64,652
Number of restricted stock issued during period, value																									$ 220,952
Series D Warrants [Member]
Warrant exercise price per share			$ 24.30																			$ 24.30			$ 24.30
NewWarrant [Member] \| Securities Purchase Agreement [Member]
Warrant to purchase shares of common stock							20,000		100,000	100,000
Warrant exercise price per share							$ 3.50		$ 3.50	$ 3.50
NewWarrant [Member] \| Letter Agreement [Member]
Warrant to purchase shares of common stock						296,800		2,448,200
Warrant exercise price per share						$ 3.50		$ 3.50
Warrant [Member]
Common stock, shares outstanding under the plan	9,893,034		7,764,821																			7,764,821		9,893,034	7,764,821		899,542
Outstanding stock options, terminated
New stock options, exercise price	$ 0.71																							$ 0.71
Stock options issued																								2,153,214	6,877,948
Warrant [Member] \| Securities Purchase Agreement [Member]
Warrant to purchase shares of common stock																							460,000
Warrant exercise price per share																							$ 3.50
Warrant [Member] \| Letter Agreement [Member]
Warrant exercise price per share						$ 3.50		$ 3.50
Investor Warrants [Member]
Warrant to purchase shares of common stock	1,455,600																							1,455,600
Fair value of warrant																								$ 2,307,909
Broker Warrants [Member]
Warrant to purchase shares of common stock	145,560																							145,560
New Convertible Loans [Member] \| Restricted Common Stock [Member]
Number of restricted stock issued																									88,311
Number of restricted stock issued during period, value																									$ 288,648
Preferred Stock [Member]
Convertible preferred stock, authorized	1,000,000																							1,000,000
Convertible preferred stock, par value	$ 0.01																							$ 0.01
Convertible preferred stock, shares issued	1,000,000																							1,000,000
Series A Junior Participating Preferred Stock [Member]
Convertible preferred stock, shares issued
Number of stock designated			20,000																			20,000			20,000
Preferred stock, shares outstanding
Series A Convertible Preferred Stock [Member]
Convertible preferred stock, shares issued
Number of stock designated			313,960																			313,960			313,960
Preferred stock, shares outstanding
Series B Convertible Preferred Stock [Member]
Convertible preferred stock, shares issued
Number of stock designated			279,256																			279,256			279,256
Preferred stock, shares outstanding
Series C Convertible Preferred Stock [Member]
Convertible preferred stock, shares issued
Number of stock designated			88,098																			88,098			88,098
Preferred stock, shares outstanding
Series D Convertible Preferred Stock [Member]
Convertible preferred stock, authorized	850		850																			850		850	850
Convertible preferred stock, par value	$ 0.01		$ 0.01																$ 0.01			$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued	300		300																			300		300	300
Number of stock designated			850																			850			850
Preferred stock, shares outstanding	300		300																			300		300	300
Sale of stock																			843
Purchase price per units sold																			$ 1,000
Proceeds from direct offering																			$ 843,000
Warrants term																			5 years
Warrant to purchase shares of common stock																			21
Warrant exercise price per share																			$ 24.30	$ 7.50	$ 12.00
Warrants exercisable date																			May 11, 2012
Amount to be paid at any uncertain situation value per share (subject to accrued but unpaid dividends)			$ 1,000																			$ 1,000			$ 1,000
Conversion of stock into shares																			84
Stock conversion price per share																									$ 19.50
Convertible preferred stock, conversion percentage																									300.00%
Average daily trading volume																									50,000
Ownership percentage			50.00%																			50.00%			50.00%
Change in number of warrants																				20,958	17,681
Warrants outstanding																				$ 55,887	$ 34,930
Series E Convertible Preferred Stock [Member]
Number of stock designated			500																			500			500
Series G Convertible Preferred Stock [Member]
Convertible preferred stock, authorized	240,000		240,000																			240,000		240,000	240,000
Convertible preferred stock, par value	$ 0.01		$ 0.01														$ 0.01	$ 0.01				$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued	80,570		80,570																			80,570		80,570	80,570
Number of stock designated			240,000																			240,000			240,000
Preferred stock, shares outstanding	80,570		80,570																			80,570		80,570	80,570
Sale of stock																	4,844	4,844
Purchase price per units sold																	$ 150.00	$ 150.00
Proceeds from direct offering																	$ 726,600	$ 726,600
Warrants term																	3 years	3 years
Warrant to purchase shares of common stock																	1	1
Warrant exercise price per share																	$ 15.00	$ 15.00
Convertible preferred stock, conversion percentage																									12.00%
Number of common stock shares issued, shares																	1	1
Cumulative dividend rate percentage																									4.00%
Percentage of shares purchased for investment																									6.00%
Series G Convertible Preferred Stock [Member] \| Minimum [Member]
Purchase price per units sold			$ 22.50																			$ 22.50			$ 22.50
Proceeds from direct offering																									$ 2,500,000
Average daily trading volume																									334
Number of preferred stock issued upon conversion			100,000																			100,000			100,000
Series G Convertible Preferred Stock [Member] \| Maximum [Member]
Number of preferred stock issued upon conversion			250,000																			250,000			250,000
Series H Convertible Preferred Stock [Member]
Convertible preferred stock, authorized	10,000		10,000																			10,000		10,000	10,000					10,000
Convertible preferred stock, par value	$ 0.01		$ 0.01													$ 0.01						$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued	10,000		10,000																			10,000		10,000	10,000
Number of stock designated			10,000													10,000						10,000			10,000
Preferred stock, shares outstanding	10,000		10,000																			10,000		10,000	10,000
Purchase price per units sold																$ 24.08
Conversion of stock into shares																4
Number of common shares exchanged																33,334
Common stock, par value																$ 0.01
Series H2 Convertible Preferred Stock [Member]
Convertible preferred stock, authorized	21		21									21										21		21	21
Convertible preferred stock, par value	$ 0.01		$ 0.01									$ 0.01										$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued	21		21									21										21		21	21
Number of stock designated			21									21										21			21
Preferred stock, shares outstanding	21		21																			21		21	21
Purchase price per units sold												$ 7.50
Conversion of stock into shares												3,334
Number of common shares exchanged												70,000
Common stock, par value												$ 0.01
Series J Convertible Preferred Stock [Member]
Convertible preferred stock, authorized	6,250		6,250																			6,250		6,250	6,250
Convertible preferred stock, par value	$ 0.01		$ 0.01										$ 0.01	$ 0.01	$ 0.01							$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued	3,458		3,458																			3,458		3,458	3,458
Number of stock designated			6,250																			6,250			6,250
Preferred stock, shares outstanding	3,458		3,458																			3,458		3,458	3,458
Sale of stock													5,087.5	5,087.5	5,087.5
Purchase price per units sold			$ 24.00										$ 400.00	$ 400.00	$ 400.00							$ 24.00			$ 24.00
Proceeds from direct offering													$ 2,034,700	$ 2,034,700	$ 2,034,700
Warrant to purchase shares of common stock													34	34	34
Warrant exercise price per share													$ 12.00	$ 12.00	$ 12.00
Proceeds from convertible preferred stock																									$ 250,000
Conversion of stock into shares													34	34	34										34
Average daily trading volume																									1,667
Number of shares issued upon conversion														34	34
Series K Convertible Preferred Stock [Member]
Convertible preferred stock, authorized	15,000		15,000																			15,000		15,000	15,000
Convertible preferred stock, par value	$ 0.01		$ 0.01																			$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued	6,880		6,880																			6,880		6,880	6,880
Number of stock designated			15,000																			15,000			15,000
Preferred stock, shares outstanding	6,880		6,880																			6,880		6,880	6,880
Purchase price per units sold			$ 24.00																			$ 24.00			$ 24.00
Proceeds from direct offering																									$ 2,500,000
Conversion of stock into shares																									34
Average daily trading volume																									1,667
Value of shares invested in private placements																									$ 100,000
Series AA Convertible Preferred Stock [Member]
Convertible preferred stock, authorized	10,000		10,000																			10,000		10,000	10,000
Convertible preferred stock, par value	$ 0.01		$ 0.01																			$ 0.01		$ 0.01	$ 0.01
Convertible preferred stock, shares issued	7,939		6,499																			6,499		7,939	6,499
Number of stock designated			10,000																			10,000			10,000
Preferred stock, shares outstanding	7,939		6,499																			6,499		7,939	6,499
Number of common stock shares issued, shares																								81,767	76,361
Cumulative dividend rate percentage																								8.00%
Number of preferred stock issued upon conversion	16																							16
Number of shares issued upon conversion, value																								$ 16,000
Debt converted principal amount																									$ 12,688,634
Debt converted of shares																									5,075.40
Debt conversion price per share																										$ 2.50
Number of shares issued, value																								$ 205,100	$ 258,211
Series AA Convertible Preferred Stock [Member] \| Securities Purchase Agreement [Member]
Convertible preferred stock, par value									$ 0.01	$ 0.01
Sale of stock									100	100
Cumulative dividend rate percentage																									8.00%
Number of preferred stock issued upon conversion									1,000	1,000
Sale of stock, amount									$ 250,000	$ 250,000
Series AA Convertible Preferred Stock [Member] \| Securities Purchase Agreement [Member] \| Accredited Investor [Member]
Convertible preferred stock, par value																							$ 0.01
Sale of stock							20															695	460
Warrant to purchase shares of common stock			695,000																			695,000			695,000
Warrant exercise price per share			$ 3.50																			$ 3.50			$ 3.50
Number of preferred stock issued upon conversion			1,000																			1,000	1,000		1,000
Common stock, par value			$ 0.01																			$ 0.01			$ 0.01
Sale of stock, amount							$ 50,000															$ 1,738,000	$ 1,150,000
Series AA Convertible Preferred Stock [Member] \| Securities Purchase Agreement [Member] \| Two Investors [Member]
Sale of stock																						83
Warrant to purchase shares of common stock			82,333																			82,333			82,333
Fair value of warrant																						$ 358,932
Series AA Convertible Preferred Stock [Member] \| Securities Purchase Agreement [Member] \| Placement Agent [Member]
Warrant to purchase shares of common stock	145,560		148,160																			148,160		145,560	148,160
Fair value of warrant																						$ 277,277		$ 405,557
Cash fees																								$ 363,819
Series AA Convertible Preferred Stock [Member] \| Securities Purchase Agreement [Member] \| Accredited Investors [Member]
Sale of stock																								1,456
Warrant to purchase shares of common stock	1,455,600																							1,455,600
Warrant exercise price per share	$ 3.50																							$ 3.50
Number of preferred stock issued upon conversion	1,000																							1,000
Common stock, par value	$ 0.01																							$ 0.01
Sale of stock, amount																								$ 3,600,000
Series AA Convertible Preferred Stock [Member] \| Letter Agreement [Member]
Proceeds from warrants issued						$ 10,236
Debt converted principal amount								$ 6,220,500
Debt converted of shares						2,200		2,448.20
Debt conversion price per share						$ 2.50		$ 2.50
Fair value recorded as other charges						$ 312,637
Warrant exercise price increase						$ 15.00
Warrant exercise price decrease						$ 3.50
Number of warrants held by investor						29,167
Series AA Convertible Preferred Stock [Member] \| Letter Agreement [Member] \| Accredited Investor [Member]
Convertible preferred stock, par value						$ 2,500
Warrants term						5 years
Warrant exercise price per share						$ 3.50
Number of warrants exercised						110,833
Number of common stock shares issued, shares						110.8
Fair value recorded as other charges						$ 340,257
Series AA Convertible Preferred Stock [Member] \| Restricted Common Stock [Member]
Conversion of stock into shares																									44
Cumulative dividend rate percentage																									8.00%
Number of preferred stock issued upon conversion			44,000																			44,000			44,000
Number of restricted stock issued																									76,361
Number of restricted stock issued during period, value																									$ 258,221
Convertible Preferred Stock [Member]
Adjusted beneficial conversion feature value for deemed dividend																								$ 2,653,344	12,881,899
Series AA Preferred Stock with Warrants [Member] \| Loan Agreements [Member]
Deemed dividend additional paid in capital			$ 5,113																			$ 5,113			$ 5,113
Series AA Units [Member]
Reduction in exercise price amount									$ 207,899