FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  DAMASIO JOSEPH LUIS JR
 2. Date of Event Requiring Statement (Month/Day/Year)
04/10/2017		 3. Issuer Name and Ticker or Trading Symbol
PRESSURE BIOSCIENCES INC [PBIO]
(Last)
(First)
(Middle)
14 NORFOLK AVENUE		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
VP of FINANCE and CFO
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

SOUTH EASTON, MA 02375		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
COMMON STOCK 210
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
NON-QUALIFIED STOCK OPTIONS 12/31/2015(1) 12/31/2025 COMMON STOCK 100,000 $ 0.4 D  
NON-QUALIFIED STOCK OPTIONS 03/16/2017(1) 03/16/2027 COMMON STOCK 60,000 $ 0.28 D  
NON-QUALIFIED STOCK OPTIONS 03/31/2017(1) 03/31/2027 COMMON STOCK 100,000 $ 0.28 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
DAMASIO JOSEPH LUIS JR
14 NORFOLK AVENUE
SOUTH EASTON, MA 02375		       VP of FINANCE and CFO  

Signatures

/s/ JOSEPH L. DAMASIO JR. 04/14/2017
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) NON-QUALIFIED OPTIONS VEST 1/36TH PER MONTH FOR 36 MONTHS, EFFECTIVE ON THE DAY OF GRANT.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

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